Osteocytes serve as a reservoir for intracellular persisting staphylococcus aureus due to the lack of defense mechanisms

HIGHLIGHTS

• who: ufeffLorenaufeff ufeffTuchscherrufeff from the Universidad de Leu00f3n, Spain have published the paper: Osteocytes Serve as a Reservoir for Intracellular Persisting ufeffStaphylococcus aureusufeff Due to the Lack of Defense Mechanisms, in the Journal: (JOURNAL)
• what: The authors compared the long-term survival of S. aureus in murine MC3T3-E1 osteoblasts and MLO-Y4 osteocytes. The authors show that osteocytes have a dual role during S. aureus infection, that is, they secrete several mediators that foster the inflammatory response but fail to eliminate intracellular S. aureus.
• how: Cells were analyzed using BD LSR Fortessa . . .
  

   

  

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