Osteogenic transdifferentiation of primary human fibroblasts to osteoblast-like cells with human platelet lysate

HIGHLIGHTS

  • who: Ferdy K. Cayami from the DepartmentDiponegoro University have published the research work: Osteogenic transdifferentiation of primary human fibroblasts to osteoblast-like cells with human platelet lysate, in the Journal: Scientific Reports Scientific Reports
  • what: For all experiments in this study osteogenic transdifferentiation was conducted with 5% platelet lysate which has been shown to optimally induce the transdifferentiation process (Supplemental Fig 5).
  • how: Showed that the osteogenic media induced osteoblast differentiation as seen by the increased expression of RUNX2 and ALP compared to the untreated MSCs (Supplemental Fig 7). The data was analyzed . . .

     

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