Outer membrane protein size and lps o-antigen define protective antibody targeting to the salmonella surface

HIGHLIGHTS

• who: C. Coral Domínguez-Medina from the Institute University of Birmingham, Birmingham , TT, UK have published the article: Outer membrane protein size and LPS O-antigen define protective antibody targeting to the Salmonella surface, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors show that this lack of cross-protection is due to the complex relationship between LPS O-Ag and OmpD. The work has been enabled by recent breakthroughs in atomistic simulations, which now permit explicit modeling of realistic outer membranes20,22-25. The studies show that although anti-STmOmpD sera recognize . . .
  

   

  

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