Over-expression of slc30a8/znt8 selectively in the mouse α cell impairs glucagon release and responses to hypoglycemia

HIGHLIGHTS

  • who: Antonia Solomou from the Hammersmith Hospital, du Cane Road, London , NN, UK have published the article: Over-expression of Slc30a8/ZnT8 selectively in the mouse α cell impairs glucagon release and responses to hypoglycemia, in the Journal: (JOURNAL)
  • what: In the case of the endocrine pancreas-restricted secretory granule zinc transporter SLC30A8/ZnT8, identified in GWA studies for T2D , this approach has been pivotal in highlighting the role of the transporter in the control of secretory granule formation and Zn2+ storage insulin secretion and hepatic clearance of the hormone . Using this approach the authors have . . .

     

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