Overcoming multidrug resistance (mdr): design, biological evaluation and molecular modelling studies of 2,4‐substituted quinazoline derivatives

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• who: ChemMedChem et al. from the (UNIVERSITY) have published the research work: Overcoming Multidrug Resistance (MDR): Design, Biological Evaluation and Molecular Modelling Studies of 2,4‐Substituted Quinazoline Derivatives, in the Journal: (JOURNAL)
• what: The authors designed and synthesized a new series of 2,4-disubstituted quinazoline derivatives with the aim of discovering new P-gp and/or BCRP inhibitors . The experiments were carried out as described by Contino et_al with minor modifications.[49] Each cell line (30,000 cells per well) was seeded into black CulturePlate 96/wells plate with 100 μL medium and . . .
  

   

  

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