Overcoming tumor resistance mechanisms in car-nk cell therapy

HIGHLIGHTS

• who: Antonio Valeri from the Huazhong University of Science and Technology, China have published the research work: Overcoming tumor resistance mechanisms in CAR-NK cell therapy, in the Journal: (JOURNAL)
• future: Research is needed to attempt more refined approaches to overexpress hTERT in terms of expression control for instance inducible promoters or transient expression as reported in CAR-T_cells which lead to improved proliferation and persistence in murine xenograft tumor models of human B-cell lymphomas . The results obtained from these studies should be analyzed considering that TIM-3 and TIGIT are also expressed in . . .
  

   

  

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