Overcoming variant mutation-related impacts on viral sequencing and detection methodologies

HIGHLIGHTS

• who: Nicole M. Nichols from the United States United States United States have published the research work: Overcoming variant mutation-related impacts on viral sequencing and detection methodologies, in the Journal: (JOURNAL)
• what: The authors demonstrate effective strategies to overcome genome mutation-related issues in sequencing and to evaluate diagnostic efficacy. The authors compared genome coverage profiles for the initial SARSCoV-2 strain, as well as the Delta and Omicron variants using several SARS-CoV-2 primer sets . The results describe how to conduct these evaluations using either commercially available control RNA templates or RNA . . .
  

   

  

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