HIGHLIGHTS
- who: Fatima-Zahra Benssouina et al. from the CNRS, INP, Inst Neurophysiopathol, France have published the Article: Overexpression of a Novel Noxo1 Mutant Increases Ros Production and Noxo1 Relocalisation, in the Journal: (JOURNAL)
- what: This study provides the first evidence that the D-box of Noxo1 modulates the normal membrane-cytoskeleton balance of Noxo1.
- how: After overexpression of these constructs in the colorectal cancer cell line Caco-2 the authors evaluated their expression using Western blot analysis. These results showed that mut1 induces a shift from short sticks pattern to a filaments pattern . . .
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