Overlapping genetic architecture between schizophrenia and neurodegenerative disorders

HIGHLIGHTS

  • who: Biology and colleagues from the Department of Neurology, Laboratory of Neurodegenerative Disorders, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, China have published the research work: Overlapping Genetic Architecture Between Schizophrenia and Neurodegenerative Disorders, in the Journal: (JOURNAL)
  • what: The study has several strengthes and limitations worth noting.
  • how: Gene expression data from the following sources were analyzed 1) RNA sequencing (RNA-seq) read counts from GenotypeTissue Expression (GTEx) v6p (Gamazon et_al 2018). Transcriptomic Atlases for LDSC-SEG To better understand how the genetic variants affected disease risk . . .

     

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