HIGHLIGHTS
- who: Sun Joo Lee from the Department of Cell Biology and Physiology and the Center for Investigation of Membrane Excitability Diseases, Washington University School of Medicine, StLouis have published the Article: Oxidation driven reversal of PIP2-dependent gating in GIRK2 channels, in the Journal: (JOURNAL)
- what: This study provides a straightforward explanation for canonical behavior in intact cells as reflecting the behavior of fully reduced proteins within the normal intracellular milieu, but with emergence of non-canonical behaviors, reflecting the consequences of protein purification, in oxidizing conditions.
- how: Similar results were obtained with . . .
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