Oxidation of quercetin and kaempferol markedly amplifies their antioxidant, cytoprotective, and anti-inflammatory properties

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SUMMARY

    Quercetin and kaempferol are among the most ubiquitous and abundant flavonoids in edible plants. The potential of Kae-BZF to protect against the pro-inflammatory effects associated Antioxidants 2023, 12, x FOR PEER REVIEW 3 of 19 with the nuclear factor kappa B (NF-kB)-activating effects of indomethacin was investigated. It should be noted that the mitochondria and cell protective effects of Que-BZF and Kae-BZF were seen at the same concentrations at which these compounds exert their antioxidant effects, suggesting that the latter would underlie their mitochondria and cell protective effects . . .

     

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