HIGHLIGHTS
- who: A Focus on NRF and colleagues from the (UNIVERSITY) have published the paper: Oxidative Stress in DNA Repeat Expansion Disorders: Unit of Muscular and Neurodegenerative Diseases Bambino Gesù Children's Hospital IRCCS Rome, in the Journal: (JOURNAL)
- what: In this review the authors examine the role that the redox imbalance plays in the pathological mechanisms of DNA expansion disorders and the recent advances antioxidant treatments particularly focusing the expression and the activity of the transcription factor the main cellular regulator of the antioxidant response. The link between oxidative stress-induced damage and polyQ mutant . . .
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