Oxime therapy for brain ache reactivation and neuroprotection after organophosphate poisoning

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  • who: Darya A. Kuznetsova et al. from the Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences have published the paper: Oxime Therapy for Brain AChE Reactivation and Neuroprotection after Organophosphate Poisoning, in the Journal: Pharmaceutics 2022, 1950 of /2022/
  • what: In this work modified cationic liposomes were developed that can penetrate through the BBB and deliver the reactivator of AChE pralidoxime chloride (2-PAM) into the brain. The aim of this study was to create new cationic liposomes loaded with 2-PAM to overcome the BBB, with a . . .

     

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