Oxtrhigh stroma fibroblasts control the invasion pattern of oral squamous cell carcinoma via erk5 signaling

HIGHLIGHTS

  • who: Liang Ding from the (UNIVERSITY) have published the Article: OXTRHigh stroma fibroblasts control the invasion pattern of oral squamous cell carcinoma via ERK5 signaling, in the Journal: (JOURNAL) of 31/08/2021
  • what: Next, the authors aimed to determine the mechanism of ERK5 activated in OXTRHigh CAFs. The analysis showed elevated ERK5, PKCu03b6, and MEK5 expression in the Gu03b1q-IP complex (Fig 6p). The authors focused on the stromal microenvironment of the highest risk OSCC with WPOI 4-5 type. The authors report the discovery of a phenotypically and functionally stromal fibroblast subpopulation accompanied . . .

     

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