HIGHLIGHTS
- who: Dan Li from the (UNIVERSITY) have published the paper: Oxytocin receptor induces mammary tumorigenesis through prolactin/p-STAT5 pathway, in the Journal: (JOURNAL)
- what: The study shows that 57% of ++Oxtr females develop ERBB2+ mammary tumors with change of PI3K-AKT, MAPK, Jak-STAT, and NF-kappa B pathways, similar to HER2+ breast cancer. The study demonstrates that PRL/p-STAT5 signaling mediates OXTR-induced mammary tumorigenesis.
- how: After tumor Official journal of the Cell Death Differentiation Association All data were presented as means u00b1 SD.
SUMMARY
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