Ozone-induced aryl hydrocarbon receptor activation controls lung inflammation via interleukin-22 modulation

HIGHLIGHTS

• who: Bernhard Ryffel from the Laboratory of Experimental and Molecular Immunology and Neurogenetics, UMR , CNRS-University of Orleans, Tokyo Medical University, Japan have published the research work: Ozone-Induced Aryl Hydrocarbon Receptor Activation Controls Lung Inflammation via Interleukin-22 Modulation, in the Journal: (JOURNAL)
• what: The authors identified an AhR ligand, the lipoxin A4, a tryptophan metabolite, which is produced after chronic exposure to ozone and induces AhR activation in the lung. Using IL-22-/-, IL-22Rα-/-, and IL-22xIL-17Rα-/- mice, the authors demonstrate the pro-inflammatory role of IL-22 during chronic ozone . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.