HIGHLIGHTS
- who: AS et al. from the United States Guangxi Medical University, China have published the research work: P14AS upregulates gene expression in the locus through competitive binding to PcG protein CBX7, in the Journal: (JOURNAL)
- what: The authors studied the impact of CBX7 on effect of P14AS on transcription of genes in the CDKN2A/2B locus systemically in details.
- how: The results showed that transient P14AS overexpression obviously upregulated the expression levels of P16 INK4A P14 ARF and P15 INK4B only in HEK293T and HCT116 cells with active CBX7 expression but not in . . .
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