P16 plays critical role in exacerbating inflammaging in high fat diet induced skin

HIGHLIGHTS

• who: Yan Liang and collaborators from the Department of Plastic Surgery, The Affiliated Friendship Plastic Surgery Hospital of Nanjing Medical University, Nanjing, Jiangsu, China have published the research: p16 Plays Critical Role in Exacerbating Inflammaging in High Fat Diet Induced Skin, in the Journal: Oxidative Medicine and Cellular Longevity of 21/Nov/2022
• what: The authors first reported that a HFD induced the aberrant activation of the NLRC4 inflammasome pathway to aggravate inflaming in skin. p16 may be a critical upstream activator of NLRC4.
• how: It is unclear if p16 activates the NLRP3 . . .
  

   

  

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