HIGHLIGHTS
- who: Kristina Löhr from the (UNIVERSITY) have published the Article: p21/CDKN1A Mediates Negative Regulation of Transcription by p53*, in the Journal: (JOURNAL) of April/25,/2003
- what: The authors show here that p53-mediated negative regulation of transcription could occur independently of apoptosis. The authors provide evidence that, at least in the cases of survivin and stathmin, negative gene regulation by p53 is not a consequence of apoptosis. Most strikingly, however, the authors show that the negative regulation of all p53-repressed genes analyzed entirely depends on the presence of p21/CDKN1A and . . .
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