P2y1 purinergic receptor modulate axon initial segment initial development

HIGHLIGHTS

  • who: Juan José Garrido from the Spain, Departamento de Química Física Aplicada, Universidad Autónoma de, Spain have published the article: P2Y1 Purinergic Receptor Modulate Axon Initial Segment Initial Development, in the Journal: (JOURNAL)
  • what: The authors show that F-actin distribution and intensity in AIS is modified after P2Y1 suppression, and actin cytoskeleton stabilization with jasplakinolide recovers ankyrinG density. Due to its relation with the P2Y1 receptor, the objective of the study was to decipher whether the purinergic receptor P2Y1 plays a role in AIS development and maintenance. The authors show that . . .

     

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