P2y6 receptor activation promotes inflammation and tissue remodeling in pulmonary fibrosis

HIGHLIGHTS

  • who: Marco Idzko from the United States Federal University of Rio de Janeiro have published the research work: P2Y6 Receptor Activation Promotes Inflammation and Tissue Remodeling in Pulmonary Fibrosis, in the Journal: (JOURNAL)
  • how: Similar results were obtained with primary human lung fibroblasts .

SUMMARY

    Idiopathic pulmonary fibrosis (IPF) is deadly lung disease, which is believed to arise from aberrant proliferation of fibrous tissue following tissue injury. Different cell types including inflammatory cells, lung fibroblasts, and abnormally activated alveolar epithelial_cells have been shown to play a prominent role in IPF pathophysiology. The . . .

     

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