P35 is a crucial player in nk cell cytotoxicity and tgf-β mediated nk cell dysfunction

HIGHLIGHTS

• who: Derek P. Wong et al. from the OH, USADepartment of Pathology, Case Western Reserve University, Cleveland, OH, USA have published the article: p35 is a crucial player in NK cell cytotoxicity and TGF-u03b2 mediated NK cell dysfunction, in the Journal: (JOURNAL) of 20/04/2023
• what: The authors show that Cdk5 and p35 are expressed in NK cells and are kinase-active. The authors show that NK cells cultured with TGF-u03b2 induce the expression of p35, while TGF-u03b2-mediated inhibition of NK cell cytotoxicity can be partially reversed through the inhibition . . .
  

   

  

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