HIGHLIGHTS
- who: Qi Chen from the Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, No, Xuefu Road, Nangang District, Harbin, Heilongjiang Province, China have published the research: P38 MAPK activated ADAM17 mediates ACE2 shedding and promotes cardiac remodeling and heart failure after myocardial infarction, in the Journal: (JOURNAL)
- what: The studies show that inhibition of ADAM17 expression reduced the shedding of ACE2, which in turn protected against adverse cardiac remodeling and the progression of heart failure. The authors demonstrate the soluble form of ACE2 can be released from the membrane via ADAM17 mediated . . .
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