P53 controls meiotic prophase progression and crossover formation

HIGHLIGHTS

  • who: Marina Marcet-Ortega et al. from the Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain have published the Article: p53 Controls Meiotic Prophase Progression and Crossover Formation, in the Journal: (JOURNAL)
  • what: The authors report a detailed analysis of the p53 role during meiotic prophase in mice spermatocytes. The authors show that the absence of p53 regulates prophase by slowing down the pachytene stage when the recombination-dependent arrest occurs.
  • how: The results are consistent with this observation since the authors did not observe any multinucleated cells in the samples . . .

     

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