P53-dependent aph-1 and pen-2 anti-apoptotic phenotype requires the integrity of the ù³-secretase complex but is independent of its activity*

HIGHLIGHTS

• who: Julie Dunys from the (UNIVERSITY) have published the research work: p53-dependent Aph-1 and Pen-2 Anti-apoptotic Phenotype Requires the Integrity of the Ù³-Secretase Complex but Is Independent of Its Activity*, in the Journal: (JOURNAL) of December/18,/2006
• what: Altogether, the experiments show that the function of Aph-1a, Aph-1b, and Pen-2 in the control of cell death is strictly dependent on the integrity of the ␥-secretase complex.
• how: Aph-1a Aph-1b and Pen-2 Anti-apoptotic Phenotype Is Fully Dependent on the Integrity of the . . .
  

   

  

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