P53 promotes ferroptosis in macrophages treated with fe3o4 nanoparticles

HIGHLIGHTS

  • who: Posted Date, March and Read Full, License from the Yangzhou University have published the research work: p53 Promotes Ferroptosis in Macrophages Treated with Fe3O4 Nanoparticles, in the Journal: (JOURNAL)
  • what: The authors exposed macrophages to synthesized Fe3O4 NPs (100 nm in diameter) and determined the effects of NPs in inducing cell death by RNA sequencing.

SUMMARY

    Background: Fe3O4 nanoparticles (NPs, also known as iron oxide NPs; IONPs) have high biocompatibility and low biotoxicity. NP biodistribution is determined by macrophage capture in_vivo, and recently, the induction of macrophage polarization into the . . .

     

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