P53 wild-type colorectal cancer cells that express a fetal gene signature are associated with metastasis and poor prognosis

HIGHLIGHTS

  • who: Laura Solu00e9 from the Institut Autonomous University have published the Article: p53 wild-type colorectal cancer cells that express a fetal gene signature are associated with metastasis and poor prognosis, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors propose that functional p53 through p21 allows cells to recover from DNA damage under specific conditions, whereas p53 mutant cells continue proliferating leading to irreparable damage and apoptotic death. The aim of this study was to determine the impact of sublethal CT in colorectal cancer cells.
  • how: The authors studied whether YAP1 . . .

     

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