P57kip2 regulates actin dynamics by binding and translocating lim-kinase 1 to the nucleus*

HIGHLIGHTS

  • who: Tomotaka Yokoo from the (UNIVERSITY) have published the Article: p57Kip2 Regulates Actin Dynamics by Binding and Translocating LIM-kinase 1 to the Nucleus*, in the Journal: (JOURNAL) of August/22,/2003
  • what: The authors demonstrate that p57 regulates actin dynamics by binding and translocating LIMK-1 from the cytoplasm into the nucleus, which in turn results in a reorganization of actin fiber. Based on the results , the authors propose the following model (Fig 5).
  • how: Interaction of endogenous p57 to LIMK-1 was also demonstrated in osteoblastic cells induced to differentiation by . . .

     

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