HIGHLIGHTS
- who: Ji In Kang and collaborators from the Department of Biomolecular Science, University of Science and Technology, have published the Article: p62-Induced Cancer-Associated Fibroblast Activation via the Nrf2-ATF6 Pathway Promotes Lung Tumorigenesis, in the Journal: Cancers 2021, x of 20/02/2021
- what: The authors focused on the activity of Nrf2 and ATF6, because their transcriptional activities increased more than 5-fold during CAF activation. In contrast to recent findings, which suggested that p62 acted as a tumor suppressor in CAFs , this study showed that p62 acted as a tumor inducer that . . .
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