Pad2-mediated citrullination contributes to efficient oligodendrocyte differentiation and myelination

HIGHLIGHTS

• who: Ana Mendanha Falcão from the Department the City University of USA have published the research work: PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination, in the Journal: (JOURNAL) of April/23,/2019
• what: Inhibition of has been suggested as therapeutic strategy for MS. Here contrast the authors show by peptidylarginine deiminase 2 (PAD2) to normal and motor function. Although Padi2 expression in OLs and its occurrence in myelin were described before (Wood et_al, 2008), the authors report its presence in OPCs and the dramatic upregulation of Padi2 in the transition from . . .
  

   

  

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