HIGHLIGHTS
- who: Hideki Furuya from the DepartmentState University have published the research: PAI-1 is a potential transcriptional silencer that supports bladder cancer cell activity, in the Journal: Scientific Reports Scientific Reports
- what: The authors initially investigated the expression of PAI-1 in a large cohort of bladder cancer tissues.
- how: To corroborate the nuclear presence of PAI-1 the authors examined PAI-1 cellular distribution in the nuclear and cytosolic fractions (Fig 2A) of UM-UC-3 and RT112 cells by immunoblot analysis. Enrichment score analysis based on RNA-seq data showed that . . .
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