HIGHLIGHTS
- who: Hevin/Sparcl and colleagues from the Center for TranslationalUniversity Medical Medical Center, Durham, North Carolina, USA have published the research work: pain receptor signaling, in the Journal: (JOURNAL) of June/20,/2012
- what: The authors show that astrocytic hevin signaling plays a critical role in maintaining chronic pain. The authors investigated the role of hevin in physiological, inflammatory, neuropathic, and postoperative pain. The authors demonstrate that re-expression of hevin in spinal cord astrocytes of KO mice lacking hevin is sufficient to reinstate neuropathic pain.
SUMMARY
Chronic pain, such as . . .
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