Palladium-catalyzed ortho-halogenations of acetanilides with n-halosuccinimides via direct sp2 c-h bond activation in ball mills

HIGHLIGHTS

  • who: Zi Liu and collaborators from the Hefei National Laboratory for Physical Sciences at Microscale and Department of Chemistry, University of Science and Technology of, PR have published the research work: Palladium-catalyzed ortho-halogenations of acetanilides with N-halosuccinimides via direct sp2 C-H bond activation in ball mills, in the Journal: (JOURNAL)

SUMMARY

    Aryl halides have been widely utilized in organic syntheses, which give access to a range of complex natural products. Traditional halogenations of aromatic compounds by direct electrophilic halogenation and Sandmeyer reaction have several drawbacks such as low regioselectivities . . .

     

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