Palmitate-induced cardiac lipotoxicity is relieved by the redox-active motif of selenot through improving mitochondrial function and regulating metabolic state

HIGHLIGHTS

• who: Carmine Rocca and colleagues from the (DiBEST), University of Calabria, Rende, Italy have published the research: Palmitate-Induced Cardiac Lipotoxicity Is Relieved by the Redox-Active Motif of SELENOT through Improving Mitochondrial Function and Regulating Metabolic State, in the Journal: (JOURNAL)
• what: More precisely, considering that the 3 of 25 CVSU motif of SELENOT carries a selenosulfide oxidoreductase that interacts with other cellular components via redox_reactions and is thus essential for SELENOT biological action, in the present study, the authors designed a small SELENOT mimetic peptide (called PSELT), encompassing the redox motif of the . . .
  

   

  

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