Pan-cancer analyses con rmed the cuproptosis-related gene fdx1 as an immunotherapy predictor and prognostic biomarker

HIGHLIGHTS

  • who: Fdx and collaborators from the MicroPharm Ltd, United Kingdom Jilin University, China have published the research: Pan-cancer analyses con rmed the cuproptosis-related gene FDX1 as an immunotherapy predictor and prognostic biomarker, in the Journal: (JOURNAL)
  • what: This study demonstrated that copper could bind to and aggregate with lipoylated TCA cyclins, which then trigger proteotoxic stress along with the loss of Fe-S cluster proteins, resulting in cell death (Li et_al, 2022). Based on the above evidence, the authors focused on the relevant mechanisms of FDX1 in wide varieties of tumors, and conducted . . .

     

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