Pan-cancer analysis reveals cooperativity of both strands of microrna that regulate tumorigenesis and patient survival

HIGHLIGHTS

• who: Ramkrishna Mitra from the Jefferson University have published the research work: Pan-cancer analysis reveals cooperativity of both strands of microRNA that regulate tumorigenesis and patient survival, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: As the results suggest overexpression of these miRNA may induce cell death or inhibit cell growth, the authors focused on the most relevant miRNA by determining which had consistent downregulation across cancers (Fig 1f). To further analyze whether the predicted miRNA-mediated pathway regulations captured the contribution of both 5p and 3p strands of individual miRNA, the authors evaluated . . .
  

   

  

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