HIGHLIGHTS
- who: Ankur Chakravarthy from the UCL Cancer Institute University College Southampton, Tremona Road, Southampton , YD, UK have published the research: Pan-cancer deconvolution of tumour composition using DNA methylation, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 10/07/2018
- what: The authors provide accurate estimates of tumour purity and cellular composition, and identify immune hot and cold tumours across a broad spectrum of cancer types profiled by The authors show that responses to PD1-blockade are associated with a transcriptional signature for hot tumours posttreatment, while the cold signature, and specifically a gene_expression module . . .
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