HIGHLIGHTS
- who: Cesar Barrabi from the Yat-sen University, China have published the article: Pancreatic beta cell ER export in health and diabetes, in the Journal: (JOURNAL)
- future: In future studies it will be interesting to examine the in_vivo function of Surf4 in a beta cell specific Surf4 knockout mouse model. the molecular mechanism of proinsulin ER export was poorly understood until recent years.
SUMMARY
Beta cell ER possesses a highly active protein synthetic, folding, and export machinery to accommodate the massive production of proinsulin and other ISG proteins. Among the four . . .
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