Pantoprazole impairs fracture healing in aged mice

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  • who: Maximilian M. Menger from the InstitutSaarland University have published the Article: Pantoprazole impairs fracture healing in aged mice, in the Journal: Scientific Reports Scientific Reports
  • what: The analysis showed a significantly enhanced number of osteoclasts at 2 weeks (p=0.037) after fracture healing in pantoprazole-treated animals. The aim of this study was to analyze the effect of pantoprazole treatment on bone healing in aged mice. Because BMP-4 expression was suppressed in pantoprazole-treated mice at 2 weeks after fracture healing, the authors propose that pantoprazole affects bone metabolism through the regulation . . .

     

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