Parabrachial nucleus astrocytes regulate wakefulness and iso fl urane anesthesia in mice

HIGHLIGHTS

  • who: January and colleagues from the University of Mississippi Medical Center, United States have published the article: Parabrachial nucleus astrocytes regulate wakefulness and iso fl urane anesthesia in mice, in the Journal: (JOURNAL)
  • what: The authors used chemogenetic approaches to manipulate the activity of PBN astrocytes and investigated their role in regulating sleep -wake behavior and isoflurane -induced general anesthesia.
  • how: The results showed that PBN astrocyte activation induced an increase in wakefulness whereas inhibition reduced total wakefulness. All the experimental procedures of this project were conducted in accordance with the guidlines of . . .

     

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