Paradoxical effects of rapamycin on experimental house dust mite-induced asthma

HIGHLIGHTS

  • who: Karin Fredriksson and collaborators from the Respiratory Divisions and Meakins-Christie Laboratories, Department of Medicine, McGill University Health Centre, Montreal, Quebec, Canada have published the article: Paradoxical Effects of Rapamycin on Experimental House Dust Mite-Induced Asthma, in the Journal: (JOURNAL) of May/25,/2012
  • what: The aim of this study was to assess whether inhibition of mTOR with rapamycin modifies disease severity in two experimental murine models of house dust mite (HDM)-induced asthma. The authors show that inhibition of mTOR signaling by rapamycin has paradoxical effects on the manifestations of HDM-induced . . .

     

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