Paraoxonase 1 gene polymorphisms in lipid oxidation and atherosclerosis development

HIGHLIGHTS

  • who: HDL cholesterol and colleagues from the Centre of Biotechnology of Sfax, Tunisia Bukovinian State Medical University have published the research: Paraoxonase 1 gene polymorphisms in lipid oxidation and atherosclerosis development, in the Journal: (JOURNAL)
  • what: When the analysis was done by only including studies that reported more than 500 CAD cases, the obtained correlation was further weakened (OR of 0.96), pointing to a possible publication bias in smaller studies published results (Wang et_al, 2011).

SUMMARY

    Even though PON1 exhibits its enzymatic activity on oxidized lipids, the exact physiological substrates . . .

     

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