Parental haplotype-specific single-cell transcriptomics reveal incomplete epigenetic reprogramming in human female germ cells

HIGHLIGHTS

• who: Ábel Vértesy from the Institutand University Medical Center, CT Utrecht, The Netherlands have published the research: Parental haplotype-specific single-cell transcriptomics reveal incomplete epigenetic reprogramming in human female germ cells, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 13/06/2017
• what: The authors show the maternal and paternal allele-specific expression of each imprinted gene (expressed by at least 3 cells) in germ cells and somatic_cells (Fig 3a and Supplementary Data 2). As control, the authors show that the promoter of DDX4 and DPPA5 are methylated in somatic_cells and demethylated in . . .
  

   

  

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