Parg suppresses tumorigenesis and downregulates genes controlling angiogenesis, inflammatory response, and immune cell recruitment

HIGHLIGHTS

  • who: Sarah Johnson from the Severely immunodeficient NSGTM mice (NODCgPrkdcandlt have published the research work: PARG suppresses tumorigenesis and downregulates genes controlling angiogenesis, inflammatory response, and immune cell recruitment, in the Journal: (JOURNAL)
  • what: The experiments compared the 3 T3-derived tumor growth in four tested groups, which were different in regard to the expression of hPARG and the exposure to doxycycline (Fig 2, panel A). As the level of parylation has been shown to affect transcription of multiple genes, the authors aimed to find which particular genes may change their expression profile due to . . .

     

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