HIGHLIGHTS
- who: Shuang Wang et al. from the College of Veterinary Medicine, Northeast Agricultural University, Harbin, China have published the research: Paricalcitol Ameliorates Acute Kidney Injury in Mice by Suppressing Oxidative Stress and Inflammation via Nrf2/HO-1 Signaling, in the Journal: (JOURNAL)
- what: Given this, in this experiment, the authors explored the effect of paricalcitol on cisplatin-induced AKI from oxidative stress and inflammation, using HO-1 inhibitors to determine whether paricalcitol exerts nephroprotective effects through the Nrf2/HO-1 signaling pathway. This study demonstrated the reno-protective effects of paricalcitol against cisplatin-induced acute . . .
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