Paricalcitol improves the angiopoietin/tie-2 and vegf/vegfr2 signaling pathways in adriamycin-induced nephropathy

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  • who: Amanda Lima Deluque et al. from the Laboratory of Renal Physiology, Department of Physiology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, SP, Brazil have published the Article: Paricalcitol Improves the Angiopoietin/Tie-2 and VEGF/VEGFR2 Signaling Pathways in Adriamycin-Induced Nephropathy, in the Journal: Nutrients 2022, 5316 of 14/Dec/2022
  • what: This work showed that paricalcitol treatment improved renal function and structure through antiproteinuric effects and glomerular and tubular protection. The study showed a reduction in the AT1 expression by paricalcitol treatment, indicating less vasoconstriction reflected in GFR and . . .

     

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