Parin5, a novel thrombin receptor antagonist modulates a streptozotocin mice model for diabetic encephalopathy

HIGHLIGHTS

  • who: Valery Golderman and colleagues from the Department of Neurology, The Chaim Sheba Medical Center, Department of Neurology and Neurosurgery, Sackler Faculty of Medicine, University have published the Article: PARIN5, a Novel Thrombin Receptor Antagonist Modulates a Streptozotocin Mice Model for Diabetic Encephalopathy, in the Journal: (JOURNAL)
  • what: The authors report behavioral changes in STZ diabetic mice, accompanied by the elevation of serum NfL levels as a highly sensitive marker for neuronal damage. The authors report a significant elevation in serum NfL, a subtle behavioral and cognitive deficit, an increased CNS intrinsic expression of coagulation . . .

     

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