Partial disturbance of microprocessor function in human stem cells carrying a heterozygous mutation in the dgcr8 gene

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  • who: Du00f3ra Reu00e9 et al. from the Institute of Enzymology, Research Center for Natural Sciences, Budapest, Hungary Doctoral School of Molecular Medicine, Semmelweis University, Budapest, Hungary have published the article: Partial Disturbance of Microprocessor Function in Human Stem Cells Carrying a Heterozygous Mutation in the DGCR8 Gene, in the Journal: Genes 2022, 1925 of /2022/
  • what: The authors genetically characterized single-cell originated progenies of the cell line and showed that DGCR8 heterozygous mutation results in only modest effect on the mRNA level but significant decrease at the protein level.
  • how: The authors . . .

     

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