Partial inhibition of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (pfkfb3) enzyme in myeloid cells does not affect atherosclerosis

HIGHLIGHTS

  • who: Judith C. Sluimer from the Sichuan University, China have published the Article: Partial Inhibition of the 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase-3 (PFKFB3) Enzyme in Myeloid Cells Does Not Affect Atherosclerosis, in the Journal: (JOURNAL)
  • what: This study assessed the effect of partial myeloid Pfkfb3 disruption on atherosclerosis in_vivo, after 12 weeks of HCD. Here, the authors show that partially decreased PFKFB3-mediated glycolysis in monocytes, macrophages and granulocytes does not affect atherogenesis. The authors show that the model does not induce Pfkfb3 knockdown in DCs. It should be noted that . . .

     

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