HIGHLIGHTS
- who: Begou00f1a Caballero-Ruiz and colleagues from the Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy have published the article: Partial Truncation of the C-Terminal Domain of PTCH1 in Cancer Enhances Autophagy and Metabolic Adaptability, in the Journal: Cancers 2023, 369 of 10/06/2017
- what: The authors report that the interaction of PTCH1 with ATG101 occurs through the region encoding amino_acids 1316-1447. The authors report a 2.3-5.85 % prevalence of mutations in the PTCH1 CTD in the stomach, colorectal and endometrial cancers, with three frequent frameshift spots that . . .
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